
T (+98) 23 352 20220
Email: international@du.ac.ir
Damghan University
University Blvd, Damghan, IR
Assistant Professor of Physiology
AUTHOR KEYWORDS: Cannabinoids; Extinction; Post-traumatic stress disorder; Win 55212-2
INDEX KEYWORDS: 2,3 dihydro 5 methyl 3 (morpholinomethyl) 6 (1 naphthoyl)pyrrolo[1,2,3 de][1,4]benzoxazine, animal experiment; animal model; anxiety; Article; conditioning; controlled study; drug effect; elevated plus maze test; fear; footshock; male; memory; memory consolidation; motor activity; nonhuman; open field test; posttraumatic stress disorder; rat; reinforcement
PUBLISHER: Iran University of Medical Sciences
DOI: 10.1080/07391102.2017.1391123
AUTHOR KEYWORDS: blood-brain barrier; erythropoietin; fluorescence spectroscopy; Gemini; thermal denaturation
PUBLISHER: Taylor and Francis Ltd.
DOI: 10.1016/j.physbeh.2017.02.012
AUTHOR KEYWORDS: Lead and ethanol co-exposure; Melatonin; Oxidative stress; Rat; Spatial memory
INDEX KEYWORDS: alcohol; catalase; drinking water; glutathione peroxidase; lead; lead acetate; malonaldehyde; melatonin; superoxide dismutase; thiobarbituric acid reactive substance; alcohol; antioxidant; catalase; glutathione peroxidase; lead; melatonin; superoxide dismutase, animal experiment; animal model; antioxidant activity; Article; atomic absorption spectrometry; comparative study; controlled study; female; hippocampus; lipid peroxidation; long term memory; male; memory disorder; Morris water maze test; nonhuman; oxidative stress; priority journal; rat; spatial learning; spatial memory; swimming; visual discrimination; age; analysis of variance; animal; chemically induced; drug administration; drug effects; maternal exposure; maze test; Memory Disorders; metabolism; newborn; pregnancy; spatial learning; Wistar rat, Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Catalase; Drug Administration Schedule; Ethanol; Female; Glutathione Peroxidase; Hippocampus; Lead; Lipid Peroxidation; Male; Maternal Exposure; Maze Learning; Melatonin; Memory Disorders; Pregnancy; Rats; Rats, Wistar; Spatial Learning; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances
PUBLISHER: Elsevier Inc.
DOI: 10.1016/j.ejphar.2017.01.005
AUTHOR KEYWORDS: Astrocyte; Epilepsy; GLT-1 transporter; Glutamine synthetase; β-estradiol
INDEX KEYWORDS: 4 aminobutyric acid; estradiol; glutamate ammonia ligase; glutamic acid; lithium; pilocarpine; sodium glucose cotransporter 1; estradiol; excitatory amino acid transporter 2; glutamate ammonia ligase; pilocarpine; Slc1a2 protein, rat, animal experiment; animal model; animal tissue; anticonvulsant activity; Article; astrocyte; cell density; chronic drug administration; clonic seizure; controlled study; drug megadose; drug screening; enzyme activity; female; hippocampus; latent period; nerve cell excitability; neuroprotection; nonhuman; protein expression; rat; animal; astrocyte; body weight; chemically induced; disease model; dose response; drug effects; metabolism; nerve cell; pathology; Seizures; Wistar rat, Animals; Astrocytes; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Excitatory Amino Acid Transporter 2; Female; Glutamate-Ammonia Ligase; Hippocampus; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures
PUBLISHER: Elsevier B.V.
AUTHOR KEYWORDS: Anxiety; Melatonin; Post-Traumatic Stress Disorder; Rats
INDEX KEYWORDS: melatonin, animal experiment; animal model; anxiety disorder; Article; controlled study; disease association; electric shock; elevated plus maze test; forced swim test; male; nonhuman; outcome assessment; posttraumatic stress disorder; rat
PUBLISHER: Semnan University of Medical Sciences
DOI: 10.1016/j.neuropharm.2016.07.005
AUTHOR KEYWORDS: CRH; HPA axis; Orexin; PTZ; Seizure; Stress
INDEX KEYWORDS: 4 aminobutyric acid; corticosterone; corticotropin releasing factor receptor 1; glutamic acid; messenger RNA; orexin; pentetrazole; 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine; aniline derivative; corticotropin releasing factor receptor; corticotropin releasing factor receptor 1; orexin; pentetrazole; pyrimidine derivative, adult; animal experiment; animal model; animal tissue; Article; blood level; brain function; brain region; controlled study; disease activity; disease association; disease duration; footshock; gene expression; lateral hypothalamus; male; molecular dynamics; molecular pathology; nonhuman; priority journal; protein determination; protein expression; protein function; rat; reverse transcription polymerase chain reaction; seizure; stress; animal; antagonists and inhibitors; biosynthesis; chemically induced; drug effects; lateral hypothalamus; mental stress; metabolism; prevention and control; psychology; seizure; Wistar rat, Aniline Compounds; Animals; Hypothalamic Area, Lateral; Male; Orexins; Pentylenetetrazole; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Seizures; Stress, Psychological
PUBLISHER: Elsevier Ltd
DOI: 10.1016/j.fct.2016.07.009
AUTHOR KEYWORDS: Ethanol; Lead; Oxidative stress; Rat; Spatial memory
INDEX KEYWORDS: alcohol; catalase; glutathione peroxidase; lead; malonaldehyde; superoxide dismutase; alcohol; catalase; drug combination; glutathione peroxidase; lead; malonaldehyde; superoxide dismutase, adult; alcohol consumption; animal experiment; animal tissue; Article; controlled study; developmental toxicity; escape behavior; female; gestation period; hippocampus; latent period; male; memory; nonhuman; oxidative stress; perinatal period; prenatal exposure; rat; spatial learning; animal; developmental disorder; drug combination; drug effects; hippocampus; lead poisoning; maze test; memory; metabolism; oxidative stress; spatial learning; Wistar rat, Animals; Catalase; Developmental Disabilities; Drug Combinations; Ethanol; Glutathione Peroxidase; Hippocampus; Lead; Lead Poisoning; Male; Malondialdehyde; Maze Learning; Memory; Oxidative Stress; Rats; Rats, Wistar; Spatial Learning; Superoxide Dismutase
PUBLISHER: Elsevier Ltd
DOI: 10.1016/j.bbr.2014.05.015
AUTHOR KEYWORDS: Chronic stress; Oxidative stress; Quercetin; Rat; Spatial memory
INDEX KEYWORDS: corticosterone; glutathione peroxidase; malonaldehyde; quercetin; superoxide dismutase; antioxidant; corticosterone; glutathione peroxidase; malonaldehyde; quercetin; superoxide dismutase, amnesia; analysis of variance; animal experiment; animal model; antioxidant activity; article; chronic stress; cognition; controlled study; corticosterone blood level; diet therapy; enzyme activity; hippocampus; immobilization stress; latent period; memory consolidation; Morris water maze test; neuroprotection; nonhuman; oxidative stress; priority journal; probe test; rat; spatial learning; training; animal; blood; complication; drug effects; exercise; male; maze test; Memory Disorders; mental stress; metabolism; neuropsychological test; procedures; psychology; spatial learning; spatial memory; time; treatment outcome; Wistar rat, Animals; Antioxidants; Corticosterone; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neuropsychological Tests; Quercetin; Rats; Rats, Wistar; Restraint, Physical; Spatial Learning; Spatial Memory; Stress, Psychological; Superoxide Dismutase; Time Factors; Treatment Outcome
PUBLISHER: Elsevier
DOI: 10.1016/j.ejphar.2014.02.041
AUTHOR KEYWORDS: 17β-estradiol; Brain derived neurotrophic factor; Ethanol; Neuroprotection; Purkinje cell
INDEX KEYWORDS: alcohol; brain derived neurotrophic factor; complementary DNA; estradiol; messenger RNA; alcohol; brain derived neurotrophic factor; central depressant agent; estradiol; neuroprotective agent, alcohol blood level; animal behavior; animal tissue; article; cell loss; cerebellum; controlled study; DNA synthesis; drug mechanism; enzyme linked immunosorbent assay; experimental locomotor activity test; female; histology; male; motor dysfunction; neuroprotection; newborn; nonhuman; open field test; perinatal period; priority journal; protein expression; Purkinje cell; rat; reverse transcription polymerase chain reaction; RNA extraction; rotarod test; animal; blood; cerebellum; drug effects; metabolism; motor activity; pathology; psychomotor performance; signal transduction, Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Cerebellum; Estradiol; Ethanol; Motor Activity; Neuroprotective Agents; Psychomotor Performance; Rats; Signal Transduction
PUBLISHER: Elsevier
DOI: 10.1016/j.physbeh.2014.02.040
AUTHOR KEYWORDS: Adult offspring; Corticosterone; Learning and memory; Morris water maze; Prenatal stress
INDEX KEYWORDS: corticosterone; corticosterone, adult; animal experiment; article; birth weight; controlled study; corticosterone blood level; female; first trimester pregnancy; food deprivation; heterogeneous sequential stress; immobilization stress; latent period; learning; male; memory; Morris water maze test; nonhuman; prenatal stress; priority journal; progeny; rat; second trimester pregnancy; spatial learning; swimming; third trimester pregnancy; water deprivation; animal; blood; complication; Learning Disorders; maze test; Memory Disorders; mental stress; neuropsychological test; pregnancy; prenatal exposure; task performance; time; Wistar rat, Animals; Birth Weight; Corticosterone; Female; Learning Disorders; Male; Maze Learning; Memory Disorders; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Stress, Psychological; Swimming; Task Performance and Analysis; Time Factors
PUBLISHER: Elsevier Inc.
AUTHOR KEYWORDS: Harmaline; Rat; Riluzole; Tremor
INDEX KEYWORDS: harmaline; riluzole, animal experiment; animal model; article; controlled study; disease duration; disease severity; drug effect; drug efficacy; experimental study; latent period; male; nonhuman; rat; treatment response; tremor; Wistar rat
PUBLISHER: Iran University of Medical Sciences
AUTHOR KEYWORDS: Kindling; Pentylenetetrazol; Pregnancy; Seizure; Stress
INDEX KEYWORDS: animal experiment; animal model; animal tissue; article; clonic seizure; controlled study; disease course; female; immobilization stress; kindling; male; nonhuman; pregnancy; rat; seizure threshold; stress; tonic clonic seizure
AUTHOR KEYWORDS: 6-Hydroxydopamine; Carnosic acid; Dopamine; Hippocampus; Neuroprotective
INDEX KEYWORDS: carnosic acid; oxidopamine; Rosmarinus officinalis extract, animal experiment; animal model; animal tissue; article; brain injury; controlled study; hippocampal CA1 region; immunohistochemistry; male; memory disorder; nervous system development; neuroprotection; nonhuman; pyramidal nerve cell; rat
PUBLISHER: Semnan University of Medical Sciences
DOI: 10.1016/j.pbb.2014.05.020
INDEX KEYWORDS: Erratum; retracted article
PUBLISHER: Elsevier Inc.
Methods: SPS&S model was used to induce PTSD in 56 male Wistar rats. Rats were restrained for 2 h, immediately followed by forced swimming for 20 min. After 15 min of recuperation, animals were exposed to diethyl ether until they lost consciousness. Thirty min later, rats received an electric foot shock in a shock chamber. Rats which were in the shock group, without experiencing SPS, only received an electrical foot shock. Animals received IP injections of WIN (two doses) or vehicle, before tests, in 3 continuous days. For PTSD induction, conditioned fear response was measured. Anxiety-like behavior was examined twice with elevated plus-maze.
Results: PTSD induction with SPS&S significantly decreased open arm time (OAT) and open arm entry (OAE) parameter, as compared to the control. WIN (0.25 mg/kg) significantly increased OAT as compared with the control.
Conclusion: WIN (0.25 mg/kg) decreased the anxiety like behavior induced by PTSD, so it seems to have antianxiety effect. © 2014, National Research Council of Canada. All rights reserved.
AUTHOR KEYWORDS: Anxiety; Cannabinoid receptors; Post-traumatic stress disorder; WIN55-212-2
INDEX KEYWORDS: cannabinoid receptor agonist; unclassified drug; win55-212-2, animal experiment; animal model; anxiety; Article; controlled study; electric shock; elevated plus maze test; fear; forced swim test; male; nonhuman; posttraumatic stress disorder; rat
PUBLISHER: Iranian Society of Physiology and Pharmacology
AUTHOR KEYWORDS: Convulsion; Epileptogenesis; Kindling development; Orexinergic system; Pentylenetetrazol
INDEX KEYWORDS: 1 (2 methyl 6 benzoxazolyl) 3 (1,5 naphthyridin 4 yl)urea; glutamic acid; lidocaine; orexin 1 receptor; orexin A; pentetrazole, amino acid brain level; animal experiment; animal model; animal tissue; article; controlled study; convulsion; drug mechanism; drug receptor binding; hippocampus; hypothalamus; kindling; lateral hypothalamus; male; nerve excitability; neuromodulation; nonhuman; rat; receptor blocking; seizure
PUBLISHER: Tehran University of Medical Sciences
DOI: 10.1016/j.nlm.2013.02.003
AUTHOR KEYWORDS: β-Estradiol; Ovariectomized rats; Post-traumatic stress disorder; Single-prolonged stress
INDEX KEYWORDS: estradiol, amygdaloid nucleus; animal experiment; animal model; article; conditioning; controlled study; dose response; drug dosage form comparison; drug effect; electric shock; estrogen activity; experimental model; fear; female; hippocampus; nonhuman; posttraumatic stress disorder; rat; sensitization; single prolonged stress model, Animals; Arousal; Conditioning, Operant; Cues; Disease Models, Animal; Electroshock; Estradiol; Fear; Female; Hippocampus; Ovariectomy; Rats; Rats, Wistar; Stress Disorders, Post-Traumatic; Stress, Psychological
AUTHOR KEYWORDS: Conditioning; Ethanol; Hippocampus; Reconsolidation
INDEX KEYWORDS: alcohol; paraformaldehyde; pentobarbital; phosphate buffered saline, analysis of variance; animal cell; animal experiment; animal model; animal tissue; article; behavior; clinical examination; conditioning; controlled study; dentate gyrus; experimental study; fear; granule cell; hippocampal CA1 region; hippocampal CA3 region; histology; male; medical research; memory; nonhuman; perfusion; rat
AUTHOR KEYWORDS: β-Estradiol; Post-Traumatic Stress Disorder; Rat; Single-Prolonged Stress
INDEX KEYWORDS: estradiol; sesame seed oil, adult animal; animal behavior; animal cell; animal experiment; animal model; animal tissue; article; conditioning; controlled study; dentate gyrus; drug effect; experimental rat; fear; footshock; hippocampal CA1 region; hippocampal CA3 region; histopathology; male; nonhuman; posttraumatic stress disorder; pyramidal nerve cell; rat; shock
DOI: 10.1016/j.ejphar.2012.08.014
AUTHOR KEYWORDS: (Rat); Cerebellum; Harmaline; Riluzole; Tremor
INDEX KEYWORDS: riluzole, animal behavior; animal experiment; animal model; animal tissue; article; ataxia; cerebellum; controlled study; dose response; drug dose comparison; drug effect; histopathology; motor performance; neuromodulation; neuroprotection; neurotransmission; nonhuman; open field test; priority journal; Purkinje cell; rat; rotarod test; tremor, Animals; Ataxia; Behavior, Animal; Cerebellum; Glutamates; Harmaline; Ion Channels; Male; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Rotarod Performance Test; Time Factors; Tremor
DOI: 10.1016/j.pbb.2012.04.008
AUTHOR KEYWORDS: Contextual fear conditioning; Ethanol; Hippocampus; Reconsolidation
INDEX KEYWORDS: alcohol; paraformaldehyde; phosphate buffered saline, acute drug administration; animal cell; animal experiment; animal tissue; apoptosis; article; cell density; controlled study; dentate gyrus; drug effect; freezing; hippocampal CA1 region; hippocampal CA3 region; hippocampus; male; memory; nerve cell; nick end labeling; nonhuman; priority journal; rat; tissue fixation; tissue section, Animals; Apoptosis; Behavior, Animal; Ethanol; Hippocampus; Male; Memory; Neurons; Rats; Rats, Wistar, Animalia; Rattus; Rattus norvegicus
AUTHOR KEYWORDS: Cerebellum; Ethanol; Oxidative stress; Purkinje cell; Rat
INDEX KEYWORDS: alcohol; catalase; glutathione peroxidase; superoxide dismutase; thiobarbituric acid reactive substance, animal experiment; animal model; animal tissue; antioxidant activity; article; brain development; cerebellum vermis; controlled study; enzyme activity; histopathology; lipid peroxidation; male; microcephaly; neurotoxicity; newborn; nonhuman; oxidative stress; Purkinje cell; rat, Rattus
DOI: 10.1016/j.pbb.2011.07.010
AUTHOR KEYWORDS: 17β-estradiol; Ethanol; Lipid peroxidation; Oxidative stress; Purkinje cell; Rat pups
INDEX KEYWORDS: alcohol; catalase; estradiol; glutathione peroxidase; superoxide dismutase; thiobarbituric acid reactive substance, animal experiment; antioxidant activity; article; behavior change; biochemistry; brain development; cerebellum; cerebellum vermis; controlled study; female; histology; locomotion; male; neuroprotection; neurotoxicity; nonhuman; oxidative stress; perinatal period; priority journal; Purkinje cell; rat; rotarod test; task performance, Animals; Animals, Newborn; Cerebellum; Estradiol; Ethanol; Male; Motor Activity; Motor Skills Disorders; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar, Rattus
AUTHOR KEYWORDS: Bone marrow stromal cells; Neurotrophic factors; Selegiline
INDEX KEYWORDS: azacitidine; brain derived neurotrophic factor; cell marker; epidermal growth factor; glial cell line derived neurotrophic factor; glial fibrillary acidic protein; microtubule associated protein 1; nerve growth factor; neuron specific nuclear protein; neurotrophin 3; neurotrophin 4; selegiline; selenium; transferrin; vimentin, article; autograft; bone marrow cell; cell count; cell culture; cell differentiation; cell fate; cell transdifferentiation; cell viability; colony forming unit; controlled study; culture medium; dose response; gene expression; immunohistochemistry; in vitro study; incubation time; mesenchymal stem cell; molecular mechanics; nerve cell lesion; nerve cell plasticity; neurofilament; neurologic disease; nonhuman; stroma cell
DOI: 10.1002/bem.20567
AUTHOR KEYWORDS: Diabetes; Pulsed electromagnetic field; Rat; Streptozocin; Wound healing
INDEX KEYWORDS: Animalia; Rattus; Rattus norvegicus, streptozocin, animal; article; electromagnetic field; experimental diabetes mellitus; injury; male; pathophysiology; radiation exposure; rat; skin; tensile strength; Wistar rat; wound healing, Animals; Diabetes Mellitus, Experimental; Electromagnetic Fields; Male; Rats; Rats, Wistar; Skin; Streptozocin; Tensile Strength; Wound Healing
DOI: 10.1016/j.nlm.2009.06.011
INDEX KEYWORDS: erratum; error
DOI: 10.1016/j.nlm.2008.10.008
AUTHOR KEYWORDS: Consolidation; Contextual fear conditioning; Glucocorticoids; Hippocampus; Learning; Long-term potentiation; Memory
INDEX KEYWORDS: corticosterone, animal experiment; article; conditioning; controlled study; excitatory postsynaptic potential; fear; hippocampus; hormone action; long term potentiation; male; memory consolidation; nonhuman; rat, Analysis of Variance; Animals; Corticosterone; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Fear; Freezing Reaction, Cataleptic; Hippocampus; Long-Term Potentiation; Male; Memory; Psychotropic Drugs; Random Allocation; Rats