
T (+98) 23 352 20220
Email: international@du.ac.ir
Damghan University
University Blvd, Damghan, IR
Assistant Professor of Biochemistry
DOI: 10.1016/j.nlm.2018.11.009
AUTHOR KEYWORDS: Anxiety; Hippocampus; Orexin receptors; Social novelty; Stress
DOI: 10.29252/ijrm.16.2.69
AUTHOR KEYWORDS: Beta catenin; Estrous cycle; Mice; Wnt signaling pathway
INDEX KEYWORDS: beta catenin; Wnt protein, adult; animal experiment; animal tissue; Article; controlled study; estrus cycle; female; gene expression; histology; mouse; nonhuman; ovary tissue; reverse transcription polymerase chain reaction; signal transduction; uterus horn; vagina cytology
DOI: 10.1007/s12640-018-9979-y
AUTHOR KEYWORDS: Folic acid; Homocysteine; Oxidative stress; Purkinje cell; Rat
DOI: 10.1016/j.pbb.2017.05.004
AUTHOR KEYWORDS: Glutamate receptor; Histamine; Orexin 2 receptor; Posterior hypothalamus; PTZ; Seizure
INDEX KEYWORDS: 6 cyano 7 nitro 2,3 quinoxalinedione; glutamic acid; histamine; pentetrazole; glutamic acid; pentetrazole, adult; animal experiment; animal model; animal tissue; Article; controlled study; drug effect; latent period; male; nonhuman; pentylenetetrazole-induced seizure; posterior hypothalamus; priority journal; rat; rat model; tonic clonic seizure; animal; chemically induced; drug effects; histamine release; hypothalamus; metabolism; pathophysiology; seizure; Wistar rat, Animals; Glutamic Acid; Histamine Release; Hypothalamus; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures
DOI: 10.1016/j.physbeh.2017.02.012
AUTHOR KEYWORDS: Lead and ethanol co-exposure; Melatonin; Oxidative stress; Rat; Spatial memory
INDEX KEYWORDS: alcohol; catalase; drinking water; glutathione peroxidase; lead; lead acetate; malonaldehyde; melatonin; superoxide dismutase; thiobarbituric acid reactive substance; alcohol; antioxidant; catalase; glutathione peroxidase; lead; melatonin; superoxide dismutase, animal experiment; animal model; antioxidant activity; Article; atomic absorption spectrometry; comparative study; controlled study; female; hippocampus; lipid peroxidation; long term memory; male; memory disorder; Morris water maze test; nonhuman; oxidative stress; priority journal; rat; spatial learning; spatial memory; swimming; visual discrimination; age; analysis of variance; animal; chemically induced; drug administration; drug effects; maternal exposure; maze test; Memory Disorders; metabolism; newborn; pregnancy; spatial learning; Wistar rat, Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Catalase; Drug Administration Schedule; Ethanol; Female; Glutathione Peroxidase; Hippocampus; Lead; Lipid Peroxidation; Male; Maternal Exposure; Maze Learning; Melatonin; Memory Disorders; Pregnancy; Rats; Rats, Wistar; Spatial Learning; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances
DOI: 10.1016/j.ejphar.2017.01.005
AUTHOR KEYWORDS: Astrocyte; Epilepsy; GLT-1 transporter; Glutamine synthetase; β-estradiol
INDEX KEYWORDS: 4 aminobutyric acid; estradiol; glutamate ammonia ligase; glutamic acid; lithium; pilocarpine; sodium glucose cotransporter 1; estradiol; excitatory amino acid transporter 2; glutamate ammonia ligase; pilocarpine; Slc1a2 protein, rat, animal experiment; animal model; animal tissue; anticonvulsant activity; Article; astrocyte; cell density; chronic drug administration; clonic seizure; controlled study; drug megadose; drug screening; enzyme activity; female; hippocampus; latent period; nerve cell excitability; neuroprotection; nonhuman; protein expression; rat; animal; astrocyte; body weight; chemically induced; disease model; dose response; drug effects; metabolism; nerve cell; pathology; Seizures; Wistar rat, Animals; Astrocytes; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Excitatory Amino Acid Transporter 2; Female; Glutamate-Ammonia Ligase; Hippocampus; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures
PUBLISHER: Elsevier B.V.
DOI: 10.1111/jog.13173
AUTHOR KEYWORDS: antioxidant enzyme; coenzyme Q10; ovary; vitrification
INDEX KEYWORDS: catalase; glutathione peroxidase; malonaldehyde; superoxide dismutase; ubidecarenone; antioxidant; catalase; glutathione peroxidase; malonaldehyde; superoxide dismutase; ubidecarenone; ubiquinone, animal cell; animal tissue; Article; controlled study; culture medium; enzyme activity; female; lipid peroxidation; metabolic parameters; mouse; nonhuman; ovary follicle; ovary tissue; total antioxidant capacity; vitrification; analogs and derivatives; animal; drug effects; enzymology; metabolism; ovary follicle, Animals; Antioxidants; Catalase; Female; Glutathione Peroxidase; Malondialdehyde; Mice; Ovarian Follicle; Superoxide Dismutase; Ubiquinone; Vitrification
DOI: 10.1080/19396368.2016.1235236
AUTHOR KEYWORDS: Coenzyme Q10; lipid peroxidation; preantral follicles; vitrification
INDEX KEYWORDS: antioxidant; catalase; glutathione peroxidase; lipid peroxide; malonaldehyde; superoxide dismutase; ubidecarenone; antioxidant; catalase; glutathione peroxidase; malonaldehyde; superoxide dismutase; ubidecarenone; ubiquinone, animal cell; antioxidant activity; Article; cell culture; cell maturation; controlled study; enzyme activity; in vitro study; lipid peroxidation; mouse; nonhuman; ovary; ovary follicle; ovary follicle cell; ovary follicle development; ovary follicle fluid; priority journal; total antioxidant capacity; vitrification; warming; analogs and derivatives; animal; drug effects; enzymology; female; metabolism; ovary follicle, Animals; Antioxidants; Catalase; Female; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Mice; Ovarian Follicle; Superoxide Dismutase; Ubiquinone; Vitrification
DOI: 10.1016/j.neuropharm.2016.07.005
AUTHOR KEYWORDS: CRH; HPA axis; Orexin; PTZ; Seizure; Stress
INDEX KEYWORDS: 4 aminobutyric acid; corticosterone; corticotropin releasing factor receptor 1; glutamic acid; messenger RNA; orexin; pentetrazole; 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine; aniline derivative; corticotropin releasing factor receptor; corticotropin releasing factor receptor 1; orexin; pentetrazole; pyrimidine derivative, adult; animal experiment; animal model; animal tissue; Article; blood level; brain function; brain region; controlled study; disease activity; disease association; disease duration; footshock; gene expression; lateral hypothalamus; male; molecular dynamics; molecular pathology; nonhuman; priority journal; protein determination; protein expression; protein function; rat; reverse transcription polymerase chain reaction; seizure; stress; animal; antagonists and inhibitors; biosynthesis; chemically induced; drug effects; lateral hypothalamus; mental stress; metabolism; prevention and control; psychology; seizure; Wistar rat, Aniline Compounds; Animals; Hypothalamic Area, Lateral; Male; Orexins; Pentylenetetrazole; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Seizures; Stress, Psychological
DOI: 10.1016/j.fct.2016.07.009
AUTHOR KEYWORDS: Ethanol; Lead; Oxidative stress; Rat; Spatial memory
INDEX KEYWORDS: alcohol; catalase; glutathione peroxidase; lead; malonaldehyde; superoxide dismutase; alcohol; catalase; drug combination; glutathione peroxidase; lead; malonaldehyde; superoxide dismutase, adult; alcohol consumption; animal experiment; animal tissue; Article; controlled study; developmental toxicity; escape behavior; female; gestation period; hippocampus; latent period; male; memory; nonhuman; oxidative stress; perinatal period; prenatal exposure; rat; spatial learning; animal; developmental disorder; drug combination; drug effects; hippocampus; lead poisoning; maze test; memory; metabolism; oxidative stress; spatial learning; Wistar rat, Animals; Catalase; Developmental Disabilities; Drug Combinations; Ethanol; Glutathione Peroxidase; Hippocampus; Lead; Lead Poisoning; Male; Malondialdehyde; Maze Learning; Memory; Oxidative Stress; Rats; Rats, Wistar; Spatial Learning; Superoxide Dismutase
DOI: 10.1016/j.physbeh.2015.06.040
AUTHOR KEYWORDS: Lead acetate; Melatonin; Oxidative stress; Purkinje cell; Rat
INDEX KEYWORDS: glutathione peroxidase; lead; melatonin; scavenger; superoxide dismutase; thiobarbituric acid reactive substance; glutathione peroxidase; lead; melatonin; neuroprotective agent; superoxide dismutase; thiobarbituric acid reactive substance, animal experiment; animal model; animal tissue; Article; cerebellum; controlled study; enzyme activity; experimental locomotor activity test; female; histopathology; lipid peroxidation; male; neuroprotection; neurotoxicity; nonhuman; oxidative stress; pregnancy; priority journal; rat; rotarod test; adverse effects; animal; drug effects; maternal exposure; metabolism; Movement Disorders; oxidative stress; pathology; pathophysiology; prenatal exposure; randomization; Wistar rat, Animals; Cerebellum; Female; Glutathione Peroxidase; Lead; Lipid Peroxidation; Maternal Exposure; Melatonin; Movement Disorders; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances
DOI: 10.1016/j.bbr.2015.03.022
AUTHOR KEYWORDS: Ethanol; Homocysteine; Melatonin; Oxidative stress; Purkinje cell; Rat
INDEX KEYWORDS: alcohol; catalase; glutathione peroxidase; homocysteine; melatonin; messenger RNA; protein Bax; protein bcl 2; sodium chloride; superoxide dismutase; thiobarbituric acid reactive substance; alcohol; Bax protein, rat; catalase; central depressant agent; glutathione peroxidase; homocysteine; melatonin; messenger RNA; neuroprotective agent; protein Bax; protein bcl 2; superoxide dismutase, adult; amino acid blood level; animal experiment; animal model; animal tissue; Article; cerebellum injury; cerebellum vermis; controlled study; drug effect; environmental exposure; enzyme activity; evening dosage; female; lipid peroxidation; locomotion; male; motor dysfunction; neuroprotection; neurotoxicity; nonhuman; oxidative stress; priority journal; protein expression; Purkinje cell; rat; rotarod test; animal; blood; cerebellum; drug effects; growth, development and aging; metabolism; oxidative stress; pathology; physiology; pregnancy; prenatal exposure; prevention and control; randomization; Wistar rat, Animals; bcl-2-Associated X Protein; Catalase; Central Nervous System Depressants; Cerebellum; Ethanol; Female; Glutathione Peroxidase; Homocysteine; Lipid Peroxidation; Locomotion; Melatonin; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats, Wistar; RNA, Messenger; Superoxide Dismutase
DOI: 10.1016/j.pbb.2015.01.006
AUTHOR KEYWORDS: GABA; Glutamate; Orexin receptor antagonist; Pentylenetetrazol; Seizures
INDEX KEYWORDS: 1 (2 methyl 6 benzoxazolyl) 3 (1,5 naphthyridin 4 yl)urea; 4 aminobutyric acid; agents interacting with transmitter, hormone or drug receptors; glutamic acid; orexin 1 receptor; orexin 2 receptor; orexin 2 receptor antagonist; unclassified drug; 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea; 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-((4-pyridinylmethyl)amino)-1-butanone; 4 aminobutyric acid; benzoxazole derivative; convulsant agent; glutamic acid; isoquinoline derivative; orexin receptor; orexin receptor antagonist; pentetrazole; pyridine derivative; urea, animal experiment; animal model; Article; behavior assessment; clinical effectiveness; clinical evaluation; comparative study; controlled study; convulsion; disease duration; dose response; hippocampus; male; neuromodulation; neurotransmission; nonhuman; pentylenetetrazole-induced seizure; priority journal; protein determination; protein expression; rat; treatment duration; analogs and derivatives; animal; antagonists and inhibitors; chemically induced; drug effects; hippocampus; metabolism; microinjection; seizure, Rattus, Animals; Benzoxazoles; Convulsants; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Isoquinolines; Male; Microinjections; Orexin Receptor Antagonists; Orexin Receptors; Pentylenetetrazole; Pyridines; Rats; Seizures; Urea
DOI: 10.1016/j.pbb.2014.05.020
INDEX KEYWORDS: Erratum; retracted article
PUBLISHER: Elsevier Inc.
DOI: 10.1016/j.bbr.2014.05.015
AUTHOR KEYWORDS: Chronic stress; Oxidative stress; Quercetin; Rat; Spatial memory
INDEX KEYWORDS: corticosterone; glutathione peroxidase; malonaldehyde; quercetin; superoxide dismutase; antioxidant; corticosterone; glutathione peroxidase; malonaldehyde; quercetin; superoxide dismutase, amnesia; analysis of variance; animal experiment; animal model; antioxidant activity; article; chronic stress; cognition; controlled study; corticosterone blood level; diet therapy; enzyme activity; hippocampus; immobilization stress; latent period; memory consolidation; Morris water maze test; neuroprotection; nonhuman; oxidative stress; priority journal; probe test; rat; spatial learning; training; animal; blood; complication; drug effects; exercise; male; maze test; Memory Disorders; mental stress; metabolism; neuropsychological test; procedures; psychology; spatial learning; spatial memory; time; treatment outcome; Wistar rat, Animals; Antioxidants; Corticosterone; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neuropsychological Tests; Quercetin; Rats; Rats, Wistar; Restraint, Physical; Spatial Learning; Spatial Memory; Stress, Psychological; Superoxide Dismutase; Time Factors; Treatment Outcome
METHODS: Isolated pre-antral follicles (140-150 µm in diameter) were divided into vitrified-warmed and fresh groups. Each group was subjected to in vitro maturation with or without ALA for 12 days, followed by adding human chronic gonadotropin to induce ovulation. In vitro fertilization was performed to evaluate their developmental competence. In parallel, the amount of ROS and TAC were assessed after 0, 24, 48, 72, and 96 h of culture by 2',7'-dichlorofluorescin assay and ferric reducing/antioxidant power assay, respectively.
RESULTS: The respective rates of survival, antrum formation, and metaphase II oocytes were significantly higher in ALA-supplemented groups compared to the groups not treated with ALA. TAC and ROS levels were significantly decreased and increased, respectively during the culture period up to 96 h in the absence of ALA in both vitrified and non-vitrified samples. However, with pretreatment of ALA, TAC levels were increased significantly and remained constant up to 96 h in vitrified-warmed pre-antral follicles, while ROS levels completely returned to the level of starting point after 96 h of culture in the presence of ALA.
CONCLUSION: Pretreatment of ALA positively influences development of pre-antral follicles in vitrified and non-vitrified samples through increasing follicular TAC level and decreasing ROS levels.
INDEX KEYWORDS: antioxidant; reactive oxygen metabolite; thioctic acid, animal; cell culture; cell differentiation; drug effects; female; human; metabolism; mouse; oocyte; ovary follicle; oxidation reduction reaction; vitrification, Animals; Antioxidants; Cell Differentiation; Cells, Cultured; Female; Humans; Mice; Oocytes; Ovarian Follicle; Oxidation-Reduction; Reactive Oxygen Species; Thioctic Acid; Vitrification
DOI: 10.1016/j.ejphar.2014.02.041
AUTHOR KEYWORDS: 17β-estradiol; Brain derived neurotrophic factor; Ethanol; Neuroprotection; Purkinje cell
INDEX KEYWORDS: alcohol; brain derived neurotrophic factor; complementary DNA; estradiol; messenger RNA; alcohol; brain derived neurotrophic factor; central depressant agent; estradiol; neuroprotective agent, alcohol blood level; animal behavior; animal tissue; article; cell loss; cerebellum; controlled study; DNA synthesis; drug mechanism; enzyme linked immunosorbent assay; experimental locomotor activity test; female; histology; male; motor dysfunction; neuroprotection; newborn; nonhuman; open field test; perinatal period; priority journal; protein expression; Purkinje cell; rat; reverse transcription polymerase chain reaction; RNA extraction; rotarod test; animal; blood; cerebellum; drug effects; metabolism; motor activity; pathology; psychomotor performance; signal transduction, Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Cerebellum; Estradiol; Ethanol; Motor Activity; Neuroprotective Agents; Psychomotor Performance; Rats; Signal Transduction
AUTHOR KEYWORDS: Antioxidant enzymes; Matrix metalloproteinases; Mesenchymal stem cells; Replicative Cellular Senescence
INDEX KEYWORDS: glutathione peroxidase; matrix metalloproteinase; superoxide dismutase; antioxidant; glutathione peroxidase; superoxide dismutase, adipose derived stem cell; animal cell; antioxidant activity; article; cell culture; cell therapy; controlled study; enzymatic assay; hematopoietic stem cell; mesenchymal stem cell; nonhuman; protein expression; rat; replicative cellular senescence; zymography; hematopoietic stem cell
DOI: 10.1111/jog.12394
AUTHOR KEYWORDS: alpha lipoic acid; ovarian tissue; oxidative status; vitrification
INDEX KEYWORDS: reactive oxygen metabolite; thioctic acid; antioxidant; reactive oxygen metabolite; thioctic acid, animal cell; article; blastocyst; cell survival; comparative study; controlled study; embryo; embryo cleavage; embryo development; female; fertilization in vitro; mouse; nonhuman; oocyte; ovary follicle; oxidative stress; thawing; vitrification; vitrified warmed ovarian tissue; vitrified warmed preantral follicle; animal; cryopreservation; drug effects; fertilization; metabolism; ovary follicle, Animals; Antioxidants; Cryopreservation; Embryonic Development; Female; Fertilization; Mice; Ovarian Follicle; Reactive Oxygen Species; Thioctic Acid; Vitrification
DOI: 10.6091/ibj.1258.2014
AUTHOR KEYWORDS: Alpha lipoic acid (ALA); Pre-antral follicle; Reactive oxygen species (ROS); Total antioxidant capacity (TAC); Vitrification
INDEX KEYWORDS: chorionic gonadotropin; dichlorodihydrofluorescein diacetate; reactive oxygen metabolite; thioctic acid, animal cell; antioxidant activity; antioxidant assay; article; blastocyte; cell culture; cell isolation; cell maturation; cell structure; cell survival; controlled study; enzyme assay; female; fertilization in vitro; in vitro study; metaphase; nonhuman; oocyte development; ovary follicle cell; ovulation; ovulation induction; oxidation; rat; vitrification
AUTHOR KEYWORDS: Alpha lipoic acid; Ovary; Preantral follicles; Vitrification
INDEX KEYWORDS: chorionic gonadotropin; thioctic acid, animal cell; animal tissue; Article; controlled study; embryo; embryo development; female; fertilization in vitro; in vitro study; intermethod comparison; male; mouse; nonhuman; oocyte maturation; ovary follicle; ovary follicle development; ovulation; preantral follicle; tissue culture; vitrification
DOI: 10.1007/s00706-013-1032-5
AUTHOR KEYWORDS: DNA; Fluorescence spectroscopy; Gold complex; Intercalation compounds; Ligand docking
DOI: 10.1016/j.ejphar.2012.08.014
AUTHOR KEYWORDS: Bone marrow; Long-term culture; Mesenchymal stem cells; Neurotrophic factors; Spontaneous differentiation
INDEX KEYWORDS: cell nucleus receptor; nestin; neurotrophic factor; tyrosine 3 monooxygenase, analysis of variance; animal cell; article; cell culture; controlled study; hematopoietic stem cell; marker gene; mesenchymal stem cell; nonhuman; protein expression; rat; reverse transcription polymerase chain reaction; statistical analysis; stem cell
AUTHOR KEYWORDS: Conditioning; Ethanol; Hippocampus; Reconsolidation
INDEX KEYWORDS: alcohol; paraformaldehyde; pentobarbital; phosphate buffered saline, analysis of variance; animal cell; animal experiment; animal model; animal tissue; article; behavior; clinical examination; conditioning; controlled study; dentate gyrus; experimental study; fear; granule cell; hippocampal CA1 region; hippocampal CA3 region; histology; male; medical research; memory; nonhuman; perfusion; rat
AUTHOR KEYWORDS: (Rat); Cerebellum; Harmaline; Riluzole; Tremor
INDEX KEYWORDS: riluzole, animal behavior; animal experiment; animal model; animal tissue; article; ataxia; cerebellum; controlled study; dose response; drug dose comparison; drug effect; histopathology; motor performance; neuromodulation; neuroprotection; neurotransmission; nonhuman; open field test; priority journal; Purkinje cell; rat; rotarod test; tremor, Animals; Ataxia; Behavior, Animal; Cerebellum; Glutamates; Harmaline; Ion Channels; Male; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Rotarod Performance Test; Time Factors; Tremor
DOI: 10.1016/j.pbb.2011.07.010
AUTHOR KEYWORDS: 17β-estradiol; Ethanol; Lipid peroxidation; Oxidative stress; Purkinje cell; Rat pups
INDEX KEYWORDS: alcohol; catalase; estradiol; glutathione peroxidase; superoxide dismutase; thiobarbituric acid reactive substance, animal experiment; antioxidant activity; article; behavior change; biochemistry; brain development; cerebellum; cerebellum vermis; controlled study; female; histology; locomotion; male; neuroprotection; neurotoxicity; nonhuman; oxidative stress; perinatal period; priority journal; Purkinje cell; rat; rotarod test; task performance, Animals; Animals, Newborn; Cerebellum; Estradiol; Ethanol; Male; Motor Activity; Motor Skills Disorders; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar, Rattus
AUTHOR KEYWORDS: Cytokines; Genomic DNAs from brucella strains; Nitrogen species; Reactive oxygen
INDEX KEYWORDS: bacterial DNA; cytokine; gamma interferon; interleukin 10; interleukin 12; live vaccine; nitrate; nitrite; nitrogen oxide; reactive nitrogen species; reactive oxygen metabolite; tumor necrosis factor alpha, animal cell; animal experiment; animal tissue; article; bacterial strain; bacterium isolate; Brucella; Brucella abortus; Brucella melitensis; calf (bovine); cell culture; controlled study; cytokine production; cytokine release; DNA base composition; Escherichia coli; female; immune response; immunomodulation; mouse; nonhuman; peritoneum macrophage; spleen cell; thymus; wild type, Animals; Brucella; Cells, Cultured; Cytokines; DNA, Bacterial; Escherichia coli; Interferon-gamma; Interleukin-10; Mice; Mice, Inbred BALB C; Nitric Oxide; Oligodeoxyribonucleotides; Reactive Nitrogen Species; Reactive Oxygen Species; Tumor Necrosis Factor-alpha